Comparing survival outcomes in TT3 (UARK2003-33 and 2006-66 combined) according to GEP70, GEP80(PB), and GEP80(BL) scores. (A) PFS (left) and OS (right) in both GEP70 low- and high-risk settings could be further discriminated by the GEP80(PB) model. Best outcomes were observed in patients with GEP70 low-risk and GEP80(PB) low-risk (LL) features, followed by patients with GEP70 high-risk and GEP80(PB) low-risk (HL) features and patients with GEP70 low-risk and GEP80(PB) high-risk (LH) features; worst outcomes were observed in patients with GEP70 high-risk and GEP80(PB) high-risk (HH) characteristics. The LH group exhibited poorer survival than the HL group; however, no significant differences were observed between the 2 groups (P = .216 and .268 for PFS and OS, respectively). (B) PFS (left) and OS (right) in both GEP70 low- and high-risk settings could be further discriminated by the GEP80(BL) model. Best outcomes were observed in patients with GEP70 low-risk and GEP80(BL) low-risk (LL) features, followed by patients with GEP70 high-risk and GEP80(BL) low-risk (HL) features and patients with GEP70 low-risk and GEP80(BL) high-risk (LH) features; worst outcomes were observed in patients with GEP70 high-risk and GEP80(BL) high-risk (HH) characteristics. The LH group exhibited poorer survival than the HL group, and, importantly, significant differences were observed between the 2 groups (P = .05 and .02 for PFS and OS, respectively).