Figure 5
![Figure 5. Siglec-9 peptide detects inflammation in PET. A representative whole-body coronal PET image of a rat intravenously injected with a 68Ga-DOTA peptide. Radioactivity uptake is clearly seen at the site of inflammation (I) but not in the surrounding muscle. In the PET image, also the heart (H), the liver (L), and the urinary tract (kidney [K] and bladder [B]) are seen. Mean time-activity curves of 3 animals from the site of inflammation, muscle, liver, bladder, plasma, and heart as well as SUVs obtained by PET imaging and ex vivo measurements 60 minutes after injection are presented on the right.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/118/13/10.1182_blood-2010-09-311076/4/zh89991178710005.jpeg?Expires=1724241694&Signature=sHR8JX6GgAAWE2jOQobUTIPIvOFpR8UwsZWguvoK~3R0SyDeHX5RQ2VPzm7smk3vMGtgTyJh~L5zjbzFbdRlPTpk5AtWP1t-yxWHcQYHAb8Hp0qs7pP3Q4fG2ebeoRjhTeKfIDLl-SDvFMtVqksVJRkMu0tUIot9IAtYmusvH7jnZAs1nQFEuqwOVHzVAqMoKnjVluhoavFPk3RoXLvE8FZI0GoBbcMcVcCIiKt3Q7JlRbtzEj1C8siWO8VovkSE5SGNJxgYCKmV8s4YDmv34zIGghcxcvl5TSkyc9N~g17epNPLSDTNvm00O-k~WaTb0kHMM19fLqW3ewZKxw1u-Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Siglec-9 peptide detects inflammation in PET. A representative whole-body coronal PET image of a rat intravenously injected with a 68Ga-DOTA peptide. Radioactivity uptake is clearly seen at the site of inflammation (I) but not in the surrounding muscle. In the PET image, also the heart (H), the liver (L), and the urinary tract (kidney [K] and bladder [B]) are seen. Mean time-activity curves of 3 animals from the site of inflammation, muscle, liver, bladder, plasma, and heart as well as SUVs obtained by PET imaging and ex vivo measurements 60 minutes after injection are presented on the right.
