Figure 1
![Protocol schema. OS, included regimen of oral (PO) methotrexate (MTX), mercaptopurine, vincristine, and dexamethasone (during the interim maintenance [IM] phases) and single delayed intensification; OD, included regimen of PO MTX, mercaptopurine, vincristine, and dexamethasone (during the IM phases) and double delayed intensification; IS, included regimen of IV MTX and vincristine (during the IM phases) and single delayed intensification; ID, included regimen of IV MTX and vincristine (during the IM phases) and double delayed intensification. *t(4;11)(q21;q23)(q34;q11), t(9;22), balanced t(1;19)(q23;p13), and hypodiploidy with < 45 chromosomes.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/118/2/10.1182_blood-2010-12-322909/4/zh89991173790001.jpeg?Expires=1720295556&Signature=FMCFcOv~YIzmKTdJGggH4hLzBiueCKAKML30Bn7y-4Yg-5eYlHRqYodfPDw8yACE5wfjfWM9t7dPwWv-ltbEmfZtBJjDaw~j01Io-P~hjaGMW206AfSSX9bBIpezaSc00pc8BQgCUKJnNVbySZF5xL0Lg8U4ZbQnkobdYFCEbvB7mXTB7qRKNh0EqHr1IpjjdxIIvFQYItH8YO4MUoO0kSme7OzWiPncNmon1vzlE1ja9w0NsjVQ61fANFRTna-lSWIy1-8O~1MyrjUklSRzIe3WqBHjQxEJMTC1NFK2-zhBdRLzwhWCIwT~~9yrMTCC5E9cXoBpeTEpVU1f-YixCg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Protocol schema. OS, included regimen of oral (PO) methotrexate (MTX), mercaptopurine, vincristine, and dexamethasone (during the interim maintenance [IM] phases) and single delayed intensification; OD, included regimen of PO MTX, mercaptopurine, vincristine, and dexamethasone (during the IM phases) and double delayed intensification; IS, included regimen of IV MTX and vincristine (during the IM phases) and single delayed intensification; ID, included regimen of IV MTX and vincristine (during the IM phases) and double delayed intensification. *t(4;11)(q21;q23)(q34;q11), t(9;22), balanced t(1;19)(q23;p13), and hypodiploidy with < 45 chromosomes.
