Individual admixture in healthy blood donors and Sickle Cell Disease patients from Minas Gerais. Admixture was estimated using the method by Pritchard et al implemented in the software Structure.¹¹  Each vertical bar represents an individual and his/her admixture proportions based on the parental populations on the left. Additional methodologic information and results are available as supplemental Methods. Structure was run using the following conditions and parameters: K = 3 (number of parental populations), burn-in period = 100 000, MCMC cycles after burn-in = 100 000, we used a priori information for the individuals from parental populations to assist the clustering (USEPOPINFO = 1), model = ADMIXTURE for the admixed individuals, α parameter was inferred for each population, GENSBACK = 2, MIGRPRIOR = 0.05, allele frequencies was assumed to be correlated.