FcγRIIa/IIb mRNA ratio on monocytes from ITP patients and controls, and changes in FcγRIIa/IIb mRNA expression levels in ITP patients before and after treatment. (A) FcγRIIa and FcγRIIb mRNA expression ratio on monocytes from ITP patients before and after treatment and controls was determined by quantitative PCR. The differences among these 3 groups were analyzed using Kruskal-Wallis test and the differences between 2 groups were analyzed using the Nemenyi test. *P < .001. (B) FcγRIIa and FcγRIIb mRNA expression levels on monocytes from ITP patients were measured before and after HD-DXM treatment. #Patients with decreased FcγRIIb mRNA expression after HD-DXM treatment. (C) After administration of HD-DXM, 18 of 23 patients had reduced FcγRIIa/IIb mRNA expression ratios, while the other 5 had similar or higher FcγRIIa/IIb mRNA expression ratios compared with those before treatment. *Patients with increased FcγRIIa/IIb mRNA ratios after HD-DXM treatment.