An integrated view of somatic CNA and sequence mutation in genes with recurrent sequence mutations across the 187 patients. Samples are displayed in columns and grouped by their corresponding ROSE clusters.¹²  Genes are shown in rows grouped by their corresponding pathways. Somatic sequence mutations are marked in orange unless they occur with a somatic deletion (which is shown in cyan). Multiple mutations within a single gene are labeled “x.” Somatic deletions and amplifications are shown in blue and red, and the shades indicate the level of CNAs