Functional classification of CLL samples in genetic subgroups. Percentages of patient samples with different p53/p21 FACS responses grouped by their genetic aberrations in (A) the original cohort and (B) the validation cohort. Dark gray, 17p deletion; light gray, sole TP53 mutation; black, 11q deletion; white, no 11q deletion, 17p deletion, or TP53 mutation.