Relationship between miR-181b expression values and time to treatment. Kaplan-Meier curves depict the clinical outcome of patients with CLL in which the 2 groups were separated on the basis of either a miRNA value dichotomized to ≤ 0.005 (A-B) or the properties defined on the basis of miR-181 expression values (C). The patient numbers were measured at the time intervals of 0, 500, 1000, 1500, 2000, and 2500 days. Log-rank P values are from Kaplan-Meier analysis.