Figure 1
![Figure 1. Reduced survival rate and hypersensitivity to lymphoma development in Nrf3-deficient mice treated with B[a]P compared with wild-type mice. (A-B) Kaplan-Meier survival curves are shown for wild-type mice (n = 34) (A) and Nrf3-deficient mice (n = 35) (B) treated or not with B[a]P. Control mice (○, ▵) and B[a]P-treated mice (●, ▴) are shown. (C) Kaplan-Meier survival curves (lymphoma-free) are shown for wild-type mice (n = 15) and Nrf3-deficient mice (n = 17) treated with B[a]P. *P < .05. **P < .01.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/117/6/10.1182_blood-2010-02-271460/4/zh89991066250001.jpeg?Expires=1722705881&Signature=M9wPJtfpLgxJRtiA5tSp836Y4k9-hGHaoYtGUyafqVZ83Nv-Kaf1QbpTnEBFKEugQ0FEQ4LqBgkTTsdWSoQOlZF4UkgzVxGP4XP0puahp63fBOb4ZcCEv~FSCvZFGLWOKWSebM7XzNa0hkE6BduDFRVNjaLb4tJGULGpreTVN1B~iVaZqvu00cjxUfom1~8FKzrSkgnYRiyB70gR7o7tRpLs9Iyx7buTKDtME2cRryW3c7yrsjk~ovhHhTRzDFGHfvYUHd4zlmUjWmZV2CmTGpxiGdAHCtB7IDuZjBDlWt6Coa-9wzHRdoiWxngVLbCcSvj-vdLDwYm5rtsz7p~CsA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Reduced survival rate and hypersensitivity to lymphoma development in Nrf3-deficient mice treated with B[a]P compared with wild-type mice. (A-B) Kaplan-Meier survival curves are shown for wild-type mice (n = 34) (A) and Nrf3-deficient mice (n = 35) (B) treated or not with B[a]P. Control mice (○, ▵) and B[a]P-treated mice (●, ▴) are shown. (C) Kaplan-Meier survival curves (lymphoma-free) are shown for wild-type mice (n = 15) and Nrf3-deficient mice (n = 17) treated with B[a]P. *P < .05. **P < .01.
