Figure 3
Figure 3. Homing and colonization of BMDCs in LLC and EMT/6 tumors after treatment with PTX or PTX in combination with either G-CSF or AMD3100. (A) C57Bl/6 mice bearing 500 mm3 LLC tumors (n = 4-5 mice per group) or (B) BALB/c mice bearing 500 mm3 EMT/6 murine breast carcinoma (n = 4-5 mice per group) were treated with PTX or PTX in combination with either G-CSF or AMD3100. Tumors were removed 3 days later and prepared as single cell suspensions for the evaluation of hemangiocytes (HEMANGIO) and MDSCs colonization of tumors using flow cytometry. *.05 > P > .01; **.01 > P > .001 from control group, unless indicated otherwise.

Homing and colonization of BMDCs in LLC and EMT/6 tumors after treatment with PTX or PTX in combination with either G-CSF or AMD3100. (A) C57Bl/6 mice bearing 500 mm3 LLC tumors (n = 4-5 mice per group) or (B) BALB/c mice bearing 500 mm3 EMT/6 murine breast carcinoma (n = 4-5 mice per group) were treated with PTX or PTX in combination with either G-CSF or AMD3100. Tumors were removed 3 days later and prepared as single cell suspensions for the evaluation of hemangiocytes (HEMANGIO) and MDSCs colonization of tumors using flow cytometry. *.05 > P > .01; **.01 > P > .001 from control group, unless indicated otherwise.

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