Figure 1
Figure 1. Modeling of blood data. Modeling of blood data using blood deuterium-to-proton enrichment curves constructed from the authors' published illustrations and the following equation, assuming a negligible PB neutrophil lifespan: blood enrichment (t)=a*[ urine enrichment curve(t−b) ] where a is a scaling factor for the differing urine and blood deuterium enrichments, b is the time interval (delay) between the 2 time-enrichment curves, and t is time. The urine enrichment curve was constructed from the authors' simple exponential model. Fitting gave a delay of 11.2 days, similar to the sum (11.1 days) of the authors' mean values for marrow transit time and PB lifespan.

Modeling of blood data. Modeling of blood data using blood deuterium-to-proton enrichment curves constructed from the authors' published illustrations and the following equation, assuming a negligible PB neutrophil lifespan: bloodenrichment(t)=a*[urine enrichmentcurve(tb)] where a is a scaling factor for the differing urine and blood deuterium enrichments, b is the time interval (delay) between the 2 time-enrichment curves, and t is time. The urine enrichment curve was constructed from the authors' simple exponential model. Fitting gave a delay of 11.2 days, similar to the sum (11.1 days) of the authors' mean values for marrow transit time and PB lifespan.

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