Figure 4.
Figure 4. AID is inducible in both WM and IgM MGUS. (A) AID expression is compared before and after CD40L/IL-4 stimulation by bulk RT-PCR. (B) Aliquots of 1000 cells/tube from unstimulated CD20+ B cells were analyzed for AID transcripts (left side of each row) or single CD20+ cells from poststimulated samples were sorted and analyzed for clonotypic and AID transcripts (right side of each row).

AID is inducible in both WM and IgM MGUS. (A) AID expression is compared before and after CD40L/IL-4 stimulation by bulk RT-PCR. (B) Aliquots of 1000 cells/tube from unstimulated CD20+ B cells were analyzed for AID transcripts (left side of each row) or single CD20+ cells from poststimulated samples were sorted and analyzed for clonotypic and AID transcripts (right side of each row).

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