Figure 1.
![Figure 1. Kinetics of vaccine-specific and bystander proliferative responses of Tmem cells following booster vaccination with TT. Six representative examples are shown. Vaccination (week 0) induces early (subjects 5, 3, and 10) and late (subjects 6, 8, and 9) TT-specific responses. Parallel kinetics were observed in the responses against 2 unrelated antigens (PPD and C albicans [C alb]) for which pre-existing immunity was evident, but no responses were detected against control antigens (Ctrl 1 and Ctrl 2) with no evident pre-existing immunity. Proliferative activity was measured by 3H-thymidine incorporation after 6 days of in vitro culture and reported for each time point as the mean value of stimulation index (SI) in triplicate cultures ± SD.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/107/7/10.1182_blood-2005-08-3255/5/zh80070693450001.jpeg?Expires=1724176753&Signature=dRiF4msvKw-qjYxpaHF~pUJue2QoUezI~aUf6suswJR~rAkjsF9Lc31nCenhzFU~24tQ-zafTC16ICu6zrY~acfqcJXx7nhSS2gt7AoRc4kpl4RIMn4eQ7qLw9MuN92UloBzkFuFoFaRJcGD2CjiRm8KAvNMVS01A2frNwWYCymAHK850m8EvmiDs1aAykYAnmp~P9ol70dHlEkRv05-KboxXN4XeFR-4-T8L2nbxQ1q~h5pI1PNsVffSBi70ht1eYgDsrMb8318lRrXMOMt-HiSq7zmQdkPdHr3agMI6rRDq~5PzZbeFztTh~TsYwxym-DbZzj8OAE1krdtoj7TLQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Kinetics of vaccine-specific and bystander proliferative responses of Tmem cells following booster vaccination with TT. Six representative examples are shown. Vaccination (week 0) induces early (subjects 5, 3, and 10) and late (subjects 6, 8, and 9) TT-specific responses. Parallel kinetics were observed in the responses against 2 unrelated antigens (PPD and C albicans [C alb]) for which pre-existing immunity was evident, but no responses were detected against control antigens (Ctrl 1 and Ctrl 2) with no evident pre-existing immunity. Proliferative activity was measured by 3H-thymidine incorporation after 6 days of in vitro culture and reported for each time point as the mean value of stimulation index (SI) in triplicate cultures ± SD.
