Competitive growth advantage of ΔHmga2 BM cells. Chimerism in peripheral blood of lethally irradiated recipient mice (glucose phosphate isomerase^a RBCs or CD45.1⁺ WBCs) after BMT with mixtures of BM cells from donors (WT mice or ΔHmga2 mice with glucose phosphate isomerase^b RBCs and CD45.2⁺ WBCs) and BM cells from mice with same allotype as recipients at the ratio of 1:1 or 1:9. (A) Donor chimerism in peripheral blood 12 weeks after BMT in primary BMT recipients. (B) Long-term peripheral blood chimerism in primary BMT recipients transplanted with BM cell mixtures consisted of ΔHmga2 donor cells and recipient-allotype cells at the ratios of 1:9 and 1:1 (n = 4-5 in each experiment). (C) Analysis of peripheral blood chimerism in primary, secondary, and tertiary transplantation recipients showed a continuous increase of proportions of ΔHmga2 blood cells in peripheral granulocytes monocytes, T cells, and B cells (n = 4-5 in each experiment). Gran. indicates granulocytes; and Mon., monocytes. *P < .05, **P < .01, ***P < .001.