Figure 3
Non–caspase-1 extracellular processing of the IL-1β precursor. The 269-aa-long IL-1β precursor is shown with the caspase-1 site at aspartic acid (D) at position 116. Extracellular protease sites are indicated by their amino acid recognition sites. The probable proteinase-3 site was derived from combinatorial methods of the specific substrate.

Non–caspase-1 extracellular processing of the IL-1β precursor. The 269-aa-long IL-1β precursor is shown with the caspase-1 site at aspartic acid (D) at position 116. Extracellular protease sites are indicated by their amino acid recognition sites. The probable proteinase-3 site was derived from combinatorial methods of the specific substrate.

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