The clustering of the major cytogenetic aberrations (gain of 1q21, hyperdiploidy, t(11;14), t(4;14), IgH split with unknown translocation partner, and deletion of 13q14) in an oncogenetic tree model of AL ± MM I and MGUS/MM I. The complete dataset with all 6 branches tested is complete in 241 of 246 AL and in 176 of 180 MGUS/MM I patients. At least one of the 6 investigated aberrations was detected in 93% (n = 224) of the evaluable AL patients and in 89% (n = 157) of the MGUS/MM I patients. The length of each horizontal edge e is proportional to −log(p_e). Bootstrap confidence values (in percentage) for the inner nodes are given, based on 500 bootstrap samples. Besides the clusters shown in this figure, t(4;14) clustered together with gain 1q21, del 13q14, and hyperdiploidy in 46% of the bootstrap samples for AL cases and in 22% for MGUS/MM I cases.