Figure 1
Expression of exhaustion-associated molecules on CD8 T cells tolerized by 3Gy TBI/anti-CD40L/allo-BMT. Splenocytes from 2C/B6 recipients of Ld+ allo-BMT with or without anti-CD40L were analyzed on day 4 post-BMT for expression of exhaustion-associated LAG-3, CTLA4 (intracellular), and 2B4 and the cytokine receptor molecules CD122 and CD127. The dotted line indicates expression level in conditioned control 2C.B6 mice that did not receive BMT. N = 5-7 mice per group.
