CB1 antagonism inhibits ocular pathologic angiogenesis. (A) Mice were treated with a single intraperitoneal injection of CB1 antagonist (0.7 mg/kg) from day P12 to P16 and were killed on day P17. New vessel tufts on the surface of retinas were stained using Isolectin GS-IB4. Overlaping photographs of the retinal segments were taken at 4× magnification and the individual images were combined as montages to reconstruct the entire retinal segment. (B) Values represent the mean ± SEM for n = 6 animals for each group (ANOVA, *P < .05, **P < .01 vs control).