Platelet reactivity predicted by differentially expressed miRNAs. Cross-validation analysis using 7 miRNAs (miR-19b, miR-34b, miR-190, miR-320a, miR-320b, miR-320c, and miR-320d) was able to predict the true epinephrine response in hyper-reactive (red) and hyporeactive (blue) platelets (r = 0.71, P = .0006801). See “Biomarker predictions” for criteria used to select the miRNAs.