Hematologic profile of PCFT^−/− mice is consistent with pancytopenia and ineffective erythropoiesis. (A) Hematologic parameters of mice with the indicated genotype at 4 to 6 weeks of age (n = 27-30 mice per cohort). Lymph indicates lymphocytes; Mono, monocytes; and Neutro, neutrophils. Additional RBCs (B) and PLT (C) parameters were assessed by FACS in the same cohorts of mice. (D) Serum concentrations of indicated soluble factors were measured in 15 to 46 mice of each genotype. All bar graph data are presented as mean ± SEM. Numbers above bars indicate P values.