Figure 6
![Figure 6. Blockade of both PD-1 and 2B4 engagement restores HIV-specific CD8+ T-cell proliferation. (A) Representative data showing expansion of proliferating CD8+ T cells (carboxyfluorescein succinimidyl ester [CFSE] low) in response to stimulation with HIV-1 Gag peptides in the presence or absence of anti-PD-L1 and/or anti-CD48 antibody blockade. (B) Summary data for expansion of HIV-specific CD8+ T cells under conditions of inhibitory pathway blockade (n = 11). Statistical comparisons were conducted using the Friedman test.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/117/18/10.1182_blood-2010-11-317297/4/zh89991170510006.jpeg?Expires=1725149730&Signature=K2uNI-8O3a5rH~uuK8vreCyiF5-KlNh3FEUsp0eZpPy5Ud7hOEb-PUQMOp8-mhYuq8kIRIs2h0ScSyAPqUZIBEoyobJkcL5vRuHkqScA-FU5Eo2uwrzHX96mdB9sVTX1rNFj3T60WOxxqVekBPhvkv~baltDEMIzrk69NZJNFrSwcbWSt2wDgVOurz6~4EheKqoD-nKd3d3LGKjMbFhUQxb8qZklLlgfCrL9OCzWO~n~Ng3HlpbmCXqBp8EAshDhC32WXIdWxDy4GNZ6-Z3tpU9YC4pk9OTlUGqNoH7wxd90G3syiXBZGEbdKKsV72H-456HvqqPDcBwGQW4bHB0hQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Blockade of both PD-1 and 2B4 engagement restores HIV-specific CD8+ T-cell proliferation. (A) Representative data showing expansion of proliferating CD8+ T cells (carboxyfluorescein succinimidyl ester [CFSE] low) in response to stimulation with HIV-1 Gag peptides in the presence or absence of anti-PD-L1 and/or anti-CD48 antibody blockade. (B) Summary data for expansion of HIV-specific CD8+ T cells under conditions of inhibitory pathway blockade (n = 11). Statistical comparisons were conducted using the Friedman test.
