The −2.8 kb GATA switch site establishes trimeH3K27 marks at the Gata2 locus. Quantitative ChIP analysis of the Gata2 locus in E14.5 fetal liver cells using antibodies to GATA-1 (A), dimeH3K4 (B), trimeH3K27 (C), and Total H3 (D). Updated model of the molecular regulation of Gata2 repression (E). Mean ± SEM. Statistical significance was assessed by 2-sided Student t test and *P ≤ .05 and **P ≤ .01.