Effect of reduced HPAEC BMPR-II expression on secretion of IL-8, IL-6, MCP-1, and ENA-78. Concentrations of IL-8 (A), IL-6, (B), MCP-1 (C), and ENA-78 (D) in supernatants from mock-transfected HPAECs or HPAECs transfected with siRNA-targeting BMPR-II or nontargeting control siRNA were determined by sandwich ELISA. Data are the mean ± SEM for a minimum of 3 independent experiments. *P < .05, compared with NTCsi-transfected cells by Student t test.