BMPR-II expression in HPAECs treated with siRNA-targeting BMPR-II or a nontargeting control siRNA. RNA was harvested from mock-transfected HPAECs or those transfected with BMPR-IIsi or NTC siRNA. Expression of BMPR-II was determined using qPCR (TaqMan; A) using primers specific for BMPR-II or Western blotting (B). For TaqMan, data are the mean ± SEM for 5 independent experiments. **P < .001, compared with HPAECs transfected with NTCsi by Student t test.