B-cell lymphoma unclassifiable, intermediate between diffuse large B-cell lymphoma and Hodgkin lymphoma. (A) Neoplastic cells resemble Hodgkin/Reed-Sternberg cells (H&E) but show retention of a full B-cell program. (B) CD20 is uniformly positive. (C) CD30 is positive, but CD15 (D) is negative. Both PAX5 (E) and OCT-2 (F) are strongly expressed. Photomicrographic images were acquired with a Nikon Eclipse 50i microscope equipped with an Olympus (Olympus America Inc) DP71 camera and software. Final image preparation was performed with Adobe Photoshop CS4 extended Version 11.0.2. Original magnifications as follows: panels A-F (400×/0.95 NA).