RELs of miRNAs in CSF of patients with PCNSL and control patients. (A) Scatterplots of expression levels of miR-21, miR-19b, miR-92a, miR-15b, miR-106b, and miR-204 in CSF samples from 23 patients with PCNSL compared with 30 control patients with various neurologic disorders. RELs of miRNAs (y-axis) are normalized to miR-24. The black horizontal lines represent median REL values. P values are indicated as determined in Mann-Whitney U statistical comparisons. (B) Scatterplots of expression levels of miR-21, miR-19b, and miR-92a in CSF samples from patients with PCNSL (n = 23) compared with subgroups of patients with inflammatory (n = 20) and miscellaneous (n = 10) CNS disorders. RELs of the miRNAs (y-axis) are normalized to miR-24. The black horizontal lines represent median REL values. Groupwise P values are indicated as determined in Kruskal-Wallis tests with Dunn multiple comparisons (*P < .05).