Figure 5
Figure 5. TFBSs significantly associated with CHE and DE_SigUP. (A) Transcription factor analysis of genes that are consistently highly expressed during erythroid maturation (CHE). Significant TFBS from Pscan output querying the JASPAR and TRANSFAC databases are shown. Green bars indicate bZIP TFBSp; red bars, ETS factor TFBS; solid bars, the TFBS was detected as significant by more than one of the 3 programs Pscan, DiRE, and CONFAC; and hashed bars, the TFBS was detected as significant by Pscan only. (B) Transcription factor analysis of genes that are significantly up-regulated during erythroid maturation (DE_SigUp). (i) Significant TFBS from Pscan output querying the JASPAR and TRANSFAC databases. (ii) Significant TFBS from DiRE output (only TFBS, which are also present in Pscan or CONFAC output or in bZIP factor family returned by Pscan search against JASPARFam database are shown). (iii) Significant TFBS from CONFAC output returned with a mean difference of the number of TFBS for each promoter between sample and control greater than 0.5 (only TFBS, which are also present in Pscan or DiRE outputs or in bZIP or ETS factor families returned by Pscan search against JASPARFam database are shown). Green bars represent bZIP TFBS; solid bars, the TFBS was detected as significant by more than one of the 3 programs Pscan, DiRE and CONFAC; and hashed bars, the TFBS was detected as significant by a single program only.

TFBSs significantly associated with CHE and DE_SigUP. (A) Transcription factor analysis of genes that are consistently highly expressed during erythroid maturation (CHE). Significant TFBS from Pscan output querying the JASPAR and TRANSFAC databases are shown. Green bars indicate bZIP TFBSp; red bars, ETS factor TFBS; solid bars, the TFBS was detected as significant by more than one of the 3 programs Pscan, DiRE, and CONFAC; and hashed bars, the TFBS was detected as significant by Pscan only. (B) Transcription factor analysis of genes that are significantly up-regulated during erythroid maturation (DE_SigUp). (i) Significant TFBS from Pscan output querying the JASPAR and TRANSFAC databases. (ii) Significant TFBS from DiRE output (only TFBS, which are also present in Pscan or CONFAC output or in bZIP factor family returned by Pscan search against JASPARFam database are shown). (iii) Significant TFBS from CONFAC output returned with a mean difference of the number of TFBS for each promoter between sample and control greater than 0.5 (only TFBS, which are also present in Pscan or DiRE outputs or in bZIP or ETS factor families returned by Pscan search against JASPARFam database are shown). Green bars represent bZIP TFBS; solid bars, the TFBS was detected as significant by more than one of the 3 programs Pscan, DiRE and CONFAC; and hashed bars, the TFBS was detected as significant by a single program only.

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