Gene profile analysis of different NK cell subsets. Gene expression profiling of sorted NK-cell subsets (n = 3 for each of 3 subsets) identified 8003 probe sets in total, using High Performance Chip Data Analysis with Bioretis database as described in supplemental Methods. Hierarchical clustering was performed with Genes@Work with Pearson correlation and center of mass. (A) All 1816 differentially expressed probe sets between CD56^dim CD62L⁺ and CD62L⁻ are shown. (B) Five functional groups of probe sets were generated with Database for Annotation, Visualization and Integrated Discovery (DAVID) from significantly differentially regulated probe sets between CD56^dim CD62L⁺ and CD62L⁻ NK-cell subsets.