Effect of washing of aged platelets before transfusion on coagulation and fibrinolysis in the lungs. Concentrations of TATc and PAA in the BALF of animals receiving saline or LPS as first hit and subsequently infusion of saline (control), supernatant (sup) of aged PLT products, or washed (wash) aged platelets. Data are presented as mean ± SEM. Supernatant of aged PLT products and not washed aged platelets increased lung coagulation and decreased fibrinolysis in LPS-primed animals as shown by an increase in TATc and decrease in PAA% in the BALF. *P < .01.