Effect of transfusion of aged platelets on lung injury in healthy and primed rats. Histologic sections of hematoxylin and eosin stained rat lungs at 20× magnification. (A) Saline control; (B) LPS control; (C) saline plus fresh PLTs day 0; (D) LPS plus PLTs day 0; (E) saline plus aged PLTs (PLTs day 5); (F) LPS plus PLTs day 5. Normal vasculature (arrows, panels A and C) neutrophils sequestrated in the vasculature (arrows, panels B,D,F).