Figure 4
Figure 4. Examples of TP53 genomic alterations detected by a dedicated quantitative QMPSF assay in DLBCL. Tumor and normal QMPSF electropherograms are indicated in blue and orange, respectively. (A) Case 10. This case showed a decrease of the fluorescence of the 10 TP53-related peaks compared with normal DNA and endogenous controls. (B) Case 92. This case displayed an aberrant electropherogram indicative of a deletion of 3 nucleotides (arrow) located within exon 8 (codon 262).

Examples of TP53 genomic alterations detected by a dedicated quantitative QMPSF assay in DLBCL. Tumor and normal QMPSF electropherograms are indicated in blue and orange, respectively. (A) Case 10. This case showed a decrease of the fluorescence of the 10 TP53-related peaks compared with normal DNA and endogenous controls. (B) Case 92. This case displayed an aberrant electropherogram indicative of a deletion of 3 nucleotides (arrow) located within exon 8 (codon 262).

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