Figure 3
Figure 3. MassArray confirms differential methylation in patients with MCL and MCL cell lines compared with NBC controls. (A-D) Heat maps of MassArray data comparing methylation in patients with MCL, MCL cell lines, and NBC controls at individual CpGs for hypermethylated genes PCDH8 and MLF1 and for hypomethylated genes HDAC1 and CD37. Rows correspond to individual samples, and columns correspond to individual CpGs. The area covered by the primer, HpaII sites, CpG islands, direction of transcription, and gene start are all indicated as tracks in the University of California Santa Cruz Browser. Scale shows relative methylation (green indicates hypomethylation; purple indicates hypermethylation).

MassArray confirms differential methylation in patients with MCL and MCL cell lines compared with NBC controls. (A-D) Heat maps of MassArray data comparing methylation in patients with MCL, MCL cell lines, and NBC controls at individual CpGs for hypermethylated genes PCDH8 and MLF1 and for hypomethylated genes HDAC1 and CD37. Rows correspond to individual samples, and columns correspond to individual CpGs. The area covered by the primer, HpaII sites, CpG islands, direction of transcription, and gene start are all indicated as tracks in the University of California Santa Cruz Browser. Scale shows relative methylation (green indicates hypomethylation; purple indicates hypermethylation).

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