Figure 6
![Figure 6. Time course of reversal from pulmonary protection after cessation of ATL146e. NY1DD mice were treated with ATL146e (10 ng/kg/minute, 3 days osmotic pump). Pulmonary parameters were measured on days 3, 4, and 7 after the cessation of ATL146e infusion. All parameters measured (vascular permeability [EBD], breathing measurements [TV, FOB], and pulmonary cell infiltrates) returned toward NY1DD baseline levels on day 4, 1 day after the cessation of ATL146e treatment, and returned to baseline levels by day 7. The solid and dashed lines represent the mean ± SEM of breathing parameters in C57BL/6 mice. Data were analyzed by 1-way ANOVA with Neuman-Keuls posttesting. *P < .05.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/116/23/10.1182_blood-2010-06-290643/4/zh89991061350006.jpeg?Expires=1724977667&Signature=J1i1luMrgRJ7qzAub48GWFFTDphrCet4BnmvwcgU2nCdf~T0mbe9JCiJZgYd63-9yRRRt5EewpKIipMbF7w0QpyEna7fFg6we7tV7PRhuyXI1QFCYa8dWs4vGeW74Cawae8vtoOmsZ2M4OXFzyCzFBeEStiw0h0xHtg7GVJYyGnoqGlwUa2CCxCZ3EgpOPy5-LLPv-a~3rhUG2jNrs3JFAlgsyjp8~ZOqRjaitR5cslwhrOD6blDJit0OTb0-pjqk0HCelM1kaiQDq5QqRIqU~3bgPbil-dGUOidqI6IiUuVynDITMuaV4FN7rh3FHNCBRwEekkpuozvq3hy3i18Uw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Time course of reversal from pulmonary protection after cessation of ATL146e. NY1DD mice were treated with ATL146e (10 ng/kg/minute, 3 days osmotic pump). Pulmonary parameters were measured on days 3, 4, and 7 after the cessation of ATL146e infusion. All parameters measured (vascular permeability [EBD], breathing measurements [TV, FOB], and pulmonary cell infiltrates) returned toward NY1DD baseline levels on day 4, 1 day after the cessation of ATL146e treatment, and returned to baseline levels by day 7. The solid and dashed lines represent the mean ± SEM of breathing parameters in C57BL/6 mice. Data were analyzed by 1-way ANOVA with Neuman-Keuls posttesting. *P < .05.
