Effect of deferasirox on cardiac T2* (♦ represents left axis; geometric mean) and LIC (■ represents right axis) in the 22 patients completing 18 months of therapy. Cardiac T2* (♦ represents left axis; geometric mean) and LIC (■ represents right axis) improved rapidly by 6 months and remained stable thereafter. Differences were significant at 6 and 12 months, but not at 18 months (P = .07).