AICAR-induced mRNA profile is irrespective of TP53 or ATM in CLL cells. (A) Cells from patients 26 and 27 (with 17p13 deletion) and (B) patients 7 and 28 (with 11q23 deletion and without ATM protein) were untreated (□) or treated with 0.5mM (▩) or 1mM AICAR (■) for 24 hours. Cells were lysed, and the mRNA levels of BIM, BNIP3, BNIP3L, HRK, MOAP1, NOXA, and PUMA were analyzed by RT-MLPA.