Distribution and cell-cycle state of endosteal and central CD150⁺CD48⁻LSK. WBM stained with anti-Sca-1, c-kit, CD150, and CD48. Dot plots show a representative analysis of CD150 and CD48 expression on endosteal (eLSK) and central (cLSK) BM (both gated for R1). Values are the mean ± SEM (5 animals). Histograms show a representative analysis of endosteal (R2) and central (R3) CD150⁺CD48⁻LSK stained with propidium iodide to determine the proportion of cycling cells. Data are the mean of 3 individual experiments ± SEM.