Figure 6
Figure 6. SOCS3 within donor T cells attenuates GVHD after allogeneic BMT. Survival by Kaplan-Meier analysis. Irradiated B6D2F1 mice received a transplant with BM and T cells from WT or SOCS3−/Δvav mice (WT, n = 16; SOCS3−/Δvav, n = 16), WT BM and SOCS3−/Δvav T cells (n = 12), or T cell–depleted SOCS3−/Δvav BM (n = 10) as described in “Hematopoietic stem cell transplantation.” Data were pooled from 3 similar experiments. *P = .045, WT versus SOCS3−/Δvav BM and T cells.

SOCS3 within donor T cells attenuates GVHD after allogeneic BMT. Survival by Kaplan-Meier analysis. Irradiated B6D2F1 mice received a transplant with BM and T cells from WT or SOCS3−/Δvav mice (WT, n = 16; SOCS3−/Δvav, n = 16), WT BM and SOCS3−/Δvav T cells (n = 12), or T cell–depleted SOCS3−/Δvav BM (n = 10) as described in “Hematopoietic stem cell transplantation.” Data were pooled from 3 similar experiments. *P = .045, WT versus SOCS3−/Δvav BM and T cells.

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