Figure 6
Figure 6. Cell-cycle analysis of erythroid progenitors (R2) and basophilic erythroblasts (R3) in day 13.5 fetal liver cells from R62W transgenic mice. (A) Cell-cycle analysis of fetal liver R2 cells from embryos carrying the RPS19R62W transgene alone (□), and from embryos carrying the RPS19R62W transgene and the Prion-Cre transgene (■). (B) Cell-cycle analysis of fetal liver R3 cells from embryos carrying the RPS19R62W transgene alone (□), and from embryos carrying the RPS19R62W transgene and the Prion-Cre transgene (■). The percentage of cells in each phase of the cell cycle is indicated on the y-axis, and the cell-cycle phases (G1, S, G2/M) are on the x-axis. Bars represent data from 4 to 6 individual embryos. (C) Cell-cycle profile of fetal liver R3 cells from embryos carrying the RPS19R62W transgene alone. (D) Cell-cycle profile of fetal liver R3 cells from embryos carrying the RPS19R62W transgene and the Prion-Cre transgene.

Cell-cycle analysis of erythroid progenitors (R2) and basophilic erythroblasts (R3) in day 13.5 fetal liver cells from R62W transgenic mice. (A) Cell-cycle analysis of fetal liver R2 cells from embryos carrying the RPS19R62W transgene alone (□), and from embryos carrying the RPS19R62W transgene and the Prion-Cre transgene (■). (B) Cell-cycle analysis of fetal liver R3 cells from embryos carrying the RPS19R62W transgene alone (□), and from embryos carrying the RPS19R62W transgene and the Prion-Cre transgene (■). The percentage of cells in each phase of the cell cycle is indicated on the y-axis, and the cell-cycle phases (G1, S, G2/M) are on the x-axis. Bars represent data from 4 to 6 individual embryos. (C) Cell-cycle profile of fetal liver R3 cells from embryos carrying the RPS19R62W transgene alone. (D) Cell-cycle profile of fetal liver R3 cells from embryos carrying the RPS19R62W transgene and the Prion-Cre transgene.

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