Increased megakaryocyte precursors and increased expression of cell cycle–related genes in megakaryocytes from Dscr1 transgenic mice. (A) Percent of bone marrow cells from wild-type (WT) or Dscr1 Tg mice that are the PreMegE (pre-megakaryocyte/erythrocyte) population identified by either CD150⁺ and CD105⁻ after gating for Lin^-C-kit⁺Sca1⁻ (left) or by CD105^loCD9^lo expression (right). (B) Quantitative polymerase chain reaction analysis of the indicated cell-cycle genes in sorted populations of small (P1) (left) and large (P2) (right) CD41⁺ cells; **P < .03; (n = 3) (gated on the live population by excluding 7AAD positive cells).