Morphologic and immunohistochemical features of case 5. (A) Histology showing a diffuse dermal infiltrate consisting of atypical medium-sized lymphocytes (hematoxylin and eosin stain; original magnification, ×400); Immunostaining for CD56 (B), granzyme B (C), and EBER signals by in situ hybridization (D; original magnifications ×400 [A,C] and ×200 [B,D]). Nikon Eclipse 50i microscope, objectives: Plan 20×/0.50 WD2.1; Plan 40×/0.75 WD0.72; Nikon DS-Fi1 camera, Nikon NIS-Elements F2.20 image acquisition software. Adobe Photoshop Elements 2.0 was used for image processing.