Figure 1
Figure 1. HIV-1 inhibits CD1d surface expression in DCs. (A-B) Human immature DCs were infected with HIV-1 BaL, stained for CD1d surface expression and intracellular expression of p24 at day 7 after infection, and analyzed by flow cytometry. CD1d MFI was calculated for infected (p24+; dashed black line) and uninfected (p24−; solid black line) cells in the culture, and for MOCK-infected cells (gray solid line). The vertical line in the dot plot indicates CD1d MFI of the p24− DC population. Data in panel B show 10 experiments with DCs from different donors. ***P < .001.

HIV-1 inhibits CD1d surface expression in DCs. (A-B) Human immature DCs were infected with HIV-1 BaL, stained for CD1d surface expression and intracellular expression of p24 at day 7 after infection, and analyzed by flow cytometry. CD1d MFI was calculated for infected (p24+; dashed black line) and uninfected (p24; solid black line) cells in the culture, and for MOCK-infected cells (gray solid line). The vertical line in the dot plot indicates CD1d MFI of the p24 DC population. Data in panel B show 10 experiments with DCs from different donors. ***P < .001.

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