Three different approaches were used to adjudicate drugs as possibly causing DITP. The central box lists the 23 agents identified using all 3 methods (plus 1 drug—amiodarone—implicated by only the first 2 methods). The categories “Both #1 & #3” and “Both #2 and #3” include the 23 patients who were identified using all 3 approaches. The numbers of drugs implicated by only 1 of the 3 approaches were 23, 15, and 482 for approaches #1, #2, and #3, respectively. AERS indicates Adverse Event Reporting System.