Figure 5
Figure 5. A peptide encoded by a SNP in HEATR1 is the minor H antigen recognized by J 47. (A) Lysis of recipient B-LCLs (♦), donor B-LCLs (○), donor B-LCLs pulsed with 1μM of peptide ISKERAEAL (■), and donor B-LCLs pulsed with 1μM of peptide ISKERAGAL (△) by the CTL clone J 47. (B) Lysis of donor B-LCLs pulsed with various concentrations of ISKERAEAL (■) or ISKERAGAL (▲) peptides. Data are at an ET of 20:1.

A peptide encoded by a SNP in HEATR1 is the minor H antigen recognized by J 47. (A) Lysis of recipient B-LCLs (♦), donor B-LCLs (○), donor B-LCLs pulsed with 1μM of peptide ISKERAEAL (■), and donor B-LCLs pulsed with 1μM of peptide ISKERAGAL (△) by the CTL clone J 47. (B) Lysis of donor B-LCLs pulsed with various concentrations of ISKERAEAL (■) or ISKERAGAL (▲) peptides. Data are at an ET of 20:1.

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