AC-loaded IFN-α DCs are powerful activators of both autologous CD8⁺ and CD4⁺ T cells. CD8⁺ T cells (A) and CD4⁺ T cells (B) were primed with autologous IFN-α DCs or IL-4 DCs, previously pulsed with allogeneic ACs. Some cultures were preincubated with anti–LOX-1 mAb before AC phagocytosis. Data represent the mean cpm of triplicate wells ± SD of one of 4 independent experiments showing similar results. Asterisks refer to given P values.