Figure 4
Figure 4. IFN-α DCs are endowed with high capability to capture ACs via LOX-1 receptor. (A-B) DCs were cocultured with PHK26-PE–labeled AC, in the presence or in absence of anti–LOX-1 mAb. Phagocytosis was evaluated by flow cytometry (A) and by CLSM (B, scale bars = 10 μm). Bars in panel A represent the mean ± SD percentage of AC-loaded DCs as double-positive cells; **P = .018 (n = 7); *P = .066 (n = 4).

IFN-α DCs are endowed with high capability to capture ACs via LOX-1 receptor. (A-B) DCs were cocultured with PHK26-PE–labeled AC, in the presence or in absence of anti–LOX-1 mAb. Phagocytosis was evaluated by flow cytometry (A) and by CLSM (B, scale bars = 10 μm). Bars in panel A represent the mean ± SD percentage of AC-loaded DCs as double-positive cells; **P = .018 (n = 7); *P = .066 (n = 4).

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