Figure 2
Aggregation of washed mouse platelets induced by recombinant murine VWF. Aggregation of washed mouse platelets (7.5 × 107/mL) was induced by the addition of wt-mVWF (A), mVWF/R1306Q (B), or mVWF/V1316M (C), all at a concentration of 3.3 μg/mL, in the absence (line I) or presence of 0.5 (line II), 1.0 (line III), or 1.5 (line IV) mg/mL ristocetin. (C inset) Aggregation of washed mouse platelets (7.5 × 107/mL) was induced by the addition of mVWF/V1316M at a concentration of 3.3 μg/mL (line A), 1.6 μg/mL (line B), or 0.8 μg/mL (line C). No ristocetin was added.
