Figure 5
![Figure 5. Readministration of AAV vectors by ATVRX in HB dogs previously exposed to AAV-2 vectors. (A-B) Canine FIX levels measured by ELISA and coagulation activity (WBCT in minutes [m]) in dogs D32 (red) and B46 (black) upon readminstration of an AAV2-cFIX vector via ATVRX. (D-E) Canine FIX levels measured by ELISA and coagulation activity (WBCT in minutes [m]) in dogs E59 (red) and H27 (black) upon readminstration of an AAV6-cFIX vector via ATVRX. (C,F) Creatinine phosphokinase (CPK) levels. x axis represents time in days.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/115/23/10.1182_blood-2009-12-261156/4/zh89991053360005.jpeg?Expires=1730491378&Signature=CYfDEbfbnh06gUB31lyxQ9Q35z~z0zLKd8g-C2LmRIUvwpT7Hfakwo7OK5GXudGIWcByxnFlDLaQTD3kMB5H4hdCugwb2tY9lN1uieIW714znZghv5N4ImVKHqK5GN~hs~phu2T4aeYeFDfDKBCJQKZFcfCNPnLroY8RuW1P17ndB275UDyYdx7QbJql4ItPBEppdYxMjFCvOOOWD2T2OVgqPjBzCdm4w5mRXjfYZFEC1ggDLaCaK6vLAVg9V70GUA-ivWQLdACM1JRnXomIWU7YBhRb38OqDqGXMPAc05Uopr81qbKUjq3xqVdpPt8abDbbCUyzPjT2YxSkFnROSw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Readministration of AAV vectors by ATVRX in HB dogs previously exposed to AAV-2 vectors. (A-B) Canine FIX levels measured by ELISA and coagulation activity (WBCT in minutes [m]) in dogs D32 (red) and B46 (black) upon readminstration of an AAV2-cFIX vector via ATVRX. (D-E) Canine FIX levels measured by ELISA and coagulation activity (WBCT in minutes [m]) in dogs E59 (red) and H27 (black) upon readminstration of an AAV6-cFIX vector via ATVRX. (C,F) Creatinine phosphokinase (CPK) levels. x axis represents time in days.
