Differentially expressed genes in a Notch1-induced mouse model of T-ALL. (A-B) SAM was applied in triplicate in 2 comparisons: polyclonal DP cells versus normal control (A) and leukemic DP cells versus polyclonal DP cells (B), with 3 different mice per group. Significant genes were selected by the following criteria: fold change ≥ 1.5 and δ value of 0.37 (polyclonal DP cells vs normal control) and 0.55 (leukemic DP cells vs polyclonal DP cells) to adjust the false discovery rate to ∼ 10%. Red or green dots represent genes that were significantly up-regulated or down-regulated in each comparison, respectively. (C) Heat-map images for the differentially expressed genes. The selected genes were classified into groups 1 to 8, based on significant levels and fold change between each of cells. Normal control (N), polyclonal DP cells (P), and leukemic DP cells (L).