Distribution of H3K4me3, H3K27me3, and EZH2 at INK4b-ARF-INK4a differs in AML cell lines with DNA methylation. ChIP-on-chip analysis of enrichment of H3K4me3 (blue), H3K27me3 (red) on chromosome 9: 21800000 to 22450000 (A) and chromosome 9: 21953000 to 22003000 (B) in AML cell lines. Top axis represents H3K4me3; and bottom axis, H3K27me3. Enrichment of EZH2 (green; C) and H3K9me3 (orange; D) at the INK4b-ARF-INK4a region in AML cell lines. Normalized enrichment data (IP/input) are plotted on a log 2 scale.