Defective peripheral lymphoid compartment in GIMAP1/CD2-cKO mice. Lymphoid subsets from spleen (A-B) and lymph nodes (C) of GIMAP1^fl/flhCD2-iCre⁻ and GIMAP1^fl/flhCD2-iCre⁺ mice were enumerated with the use of flow cytometry. (A) Representative FACS plots of splenocytes for each genotype. (B-C) Mean numbers (± SD) of cell subsets positive for the indicated surface markers (GIMAP1^fl/flhCD2-iCre⁻, n = 9; GIMAP1^fl/flhCD2-iCre⁺, n = 5). *P < .05; **P < .01; ***P < .001 (unpaired 2-tailed Student t test).